Cyanide Poisoning Sodium Thiosulfate

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sodium thiosulfate injection for cyanide poisoning
sodium thiosulfate injection. fda-approved cyanide antidote; use with infants children and adults; unique formulation with no preservatives; great value with 5-year expiry datingsodium thiosulfate - wikipediait is also often called sodium hyposulfite or hypo. sodium thiosulfate is used in gold mining water treatment analytic chemistry the development of silver-based photographic film and prints and medicine. the medical uses of sodium thiosulfate include treatment of cyanide poisoning and pityriasis.sodium thiosulfate - medical countermeasures database - chemmnithiodote (sodium nitrite and sodium thiosulfate) kit is indicated for the treatment of acute cyanide poisoning that is judged to be life-threatening. when the diagnosis of cyanide poisoning is uncertain the potentially life-threatening risks associated with nithiodote should be carefully weighed against the potential benefits especially if
sodium nitrite / sodium thiosulfate dosage guide with
sodium thiosulfate: 12.5 grams (50 ml) slow iv immediately following sodium nitrite administration-if signs of cyanide poisoning reappear repeat treatment using one-half of the original dose of both sodium nitrite and sodium thiosulfate. comments:-use with caution if the diagnosis of cyanide poisoning is uncertain.cyanide poisoning - wikipediathe evidence for sodium thiosulfate's use is based on animal studies and reports: the small quantities of cyanide present in dietary sources and in cigarette smoke are normally metabolized to relatively harmless thiocyanate by the mitochondrial enzyme rhodanese (thiosulfate cyanide sulfurtransferase) which uses thiosulfate as a substrate sodium thiosulfate intravenous advanced patient sodium thiosulfate may be used to lessen some of the side effects of cisplatin (a cancer medicine). it is also used with another medicine in the emergency treatment of cyanide poisoning. sodium thiosulfate is to be administered only by or under the immediate supervision of your doctor. before using sodium thiosulfate
cyanide poisoning - wikipedia
cyanide poisoning is poisoning that results from exposure to a number of forms of cyanide. early symptoms include headache dizziness fast heart rate shortness of breath and vomiting. this may then be followed by seizures slow heart rate low blood pressure loss of consciousness and cardiac arrest. onset of symptoms is usually within a few minutes.acute cyanide poisoning: hydroxocobalamin and sodium sodium thiosulfate acts as a sulfur donor in the conversion of cyanide to thiocyanate through rhodanese . it has poor penetration into the mitochondria which is the site of action causing slow onset . with a short half-life and delay onset sodium thiosulfate must be given in combination with other therapies .sodium thiosulfate - medical countermeasures database - chemmone method to treat cyanide poisoning involves the administration of a combination of sodium thiosulfate and sodium nitrite. sodium thiosulfate is believed to exert its antidotal effect by serving as a sulfur donor thereby increasing the rate of rhodanese catalyzed biotransformation of cyanide to thiocyanate.
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